Home > RESEARCH > Targeted Response > Micronutrients, Foods and Eye Health: A Research Overview

Micronutrients, Foods and Eye Health: A Research Overview The Ophthalmic Research journal recently published a literature overview of the most recent findings on the role of dietary micronutrients and/or supplements on vision and the prevention or delay of ocular disease, with an emphasis on cataracts. Investigators elaborated on the relationships between oxidative stress and antioxidant defenses as one of the central factors in ocular diseases. In their review, Agte and Tawardi, of the Agharkar Research Institute of Pune, India, sought to assess which “food based antioxidant nutrients might be useful in the treatment of macular degeneration and cataracts.” They explored up to date research on the roles of dietary sources of specific nutrients, supplementation with selected antioxidants or trace minerals, and reports on the effects of multiple micronutrient supplementation.  Investigators note that clinical understanding of the roles of micronutrients and eye health is relatively recent. Based on their assessment, antioxidants from food sources appear to offer the most significant health benefits without risk. Agte and Tawardi specifically highlight that carotene, lutein and zeaxanthin from fruits and vegetables are beneficial for the treatment of macular degeneration and catatracts. Utilizing PubMed and Web of Science, they also searched for articles on ocular disease and the use of vitamins A, B, C and E, minerals selenium and zinc, and Ginko biloba. Their findings were mixed. Some studies found no associations with supplement use, others observed detrimental effects, and still others observed preventive influences – particularly in high risk individuals. Agte and Tawardi conclude that while the use of supplements is not without risk and must be accurately monitored they may serve as a therapeutic complement to dietary and other measures in the treatment or prevention of ocular diseases. With regard to micronutrients from foods, Agte and Tawardi present an extensive table outlining numerous micronutrients, their predominant food sources, and their role in vision and preventative health. Clinicians who treat ocular diseases and are interested in using foods and/or supplements will find consulting this review worthwhile. Agte, v., Tawardi, K., Ophthalmic Research, 44: 166-172 (2010)

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